14° Congresso da Sociedade Latino Americana de Biomateriais, Orgãos Artificiais e Engenharia de Tecidos – SLABO
(5ª Edição do Workshop de Biomateriais, Engenharia de Tecidos e Orgãos Artificiais – OBI)
20 a 24 de Agosto de 2017 - Maresias - SP - Brasil

Luiz Henrique Catalani, He holds a Bachelor's degree in Chemistry (1979) and a Ph.D. in Organic Chemistry from the University of São Paulo (1984). Postdoctoral studies at the University of Wurzburg (Germany, 1984-1986) and Harvard University (USA, 1986-1988). He was hired by USP in 1988 where he is currently Full Professor. He is the Director of the Institute of Chemistry of the University of São Paulo since 2014. He was head of the Department of Fundamental Chemistry of IQUSP in the quadrennium 2010-2014. He was Secretary General and Vice-president of the Brazilian Society of Chemistry (2008—2016). He is Fellow of the Royal Society of Chemistry (FRSC). He is Editor of Química Nova, Coordinator of PubliSBQ (Publications of the Brazilian Chemical Society) and member of the Advisory Board of Chemical Communications and MethodsX. He is a member of ACIESP - Academy of Sciences of the State of São Paulo. He is a member of the Technology Committee of ABIQUIM (Association of Brazilian Chemical Industries). He has experience in the field of Chemistry, with emphasis on Polymers, Colloids and Biomaterials, working mainly on the following topics: biodegradable polyesters, hydrogels, nanofibers and polymer nanoparticles production and tissue engineering.

 

Tailoring properties of biodegradable polymers for tissue engineering

Luiz Henrique Catalani

Institute of Chemistry, University of São Paulo

Resumo
Our group has developed in recent years, various polymeric materials for applications in biomedical engineering, aiming at the development of scaffolds for cell growth from novel, biodegradable and bioabsorbable polymeric systems. It is intended to create conditions for the control of fundamental properties of the scaffolds for optimization of the artificial tissues creation. Thus, we propose the synthesis and study of a new class of biodegradable polymers for use in biomedicine from a family of polyesters and polyanhydrides derived from dehydroalditols. As basic processing technique, we will use electrospinning, a technique that generates porous meshes exceptionally suitable for production of thin scaffolds. The processes of cell adhesion and proliferation will be tested from culture of basic cellular types. As target tissues, we propose the production of grafts models in the reconstitution of bone defects and treatment of periodontitis, grafts for the regeneration of perforated tympanic membranes, as well as the construction of neural tissue from mesenchymal stem cells. We also propose to study the association of inorganic and/or proteic additives in order to conduct the processes of interest such as the amplification of cell adhesion and proliferation, differentiation, recruitment, stimulation of homeostasis, extracellular matrix production, and any other process for tissue regeneration

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Órgãos Artificiais e Biomecânica,Biomateriais,Normatização de Biomateriais,Liberação Controlada de Fármacos e Genes,Engenharia de Tecidos, Testes in vivo e in vitro, Medicina Regenerativa,Biopreservação,Materiais para Odontologia